Opinion
A protocol of drug and infusion fluid: Preparation, administration, compatibility, and stability in neonatal intensive unit care
Ebtisam Dribika, Nabila Hashad, Rouwaida Ramadan, Fatma S. Ertemi
Abstract :
Newborn or neonate denotes to an infant in the first few days after birth. They are not small children when it comes to medicinal use and formulation development. Neonates include term, post-term and preterm babies. The neonatal period for preterm newborn infants is defined as the day of birth through to the expected date of delivery plus 27 days [1]. The majority of drugs used in sick newborns receiving intensive care are unlicensed and off-label, exposing infants to a greater risk of adverse drug reactions (ADRs). This study is extremely important due to the presence of a variety of drug information sources if used together lead to medication errors. From this point of view, this approach is suggested to eliminate or minimize these varieties. Where the most important challenges in the neonatal intensive care unit (NICU) are proper and correct calculations and administration. Drug-related events in a hospital setting are the highest cause of recorded errors such as in the USA and UK [2]. However, there is a wide range of potential sources of drug errors including documentation, calculation, preparation, and administration [3]. Now, babies commonly receive off-label drugs, at dosages extrapolated from children or adults. Besides the lack of labelling, inappropriate formulations, polypharmacy, immature organ function and multiple illnesses further raise the risk for ADRs in neonates [2].
References
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Citation :
Dribika et al. (2022) A protocol of drug and infusion fluid: Preparation, administration, compatibility, and stability in neonatal in intensive care unit. Mediterr J Pharm Pharm Sci. 2 (2): 3-6. [Article number: 61]. https://doi.org/10.5281/zenodo.6780436