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Received date : 22-10-2023 Revised date : 18-12-2023 Accepted date : 26-12-2023 Published date : 31-12-2023

Mediterr J Pharm Pharm Sci 3 (4): 97-105, 2023

DOI: https://doi.org/10.5281/zenodo.10443250

Original Research


Assessment of knowledge and attitude of pharmacists toward the side effects of anesthetics in patients with hypertension: a cross-sectional study

Einass R. Ibraheim, Wafa M. Alshaiby, Mabrouka A. Ishrayhah, Masarra A. Ghnaia and Maiss K. Elozi



Abstract :

Pharmacists are expected to play major roles as members of diverse perioperative care teams besides implementing medication safety standards, pharmacist’s roles include optimizing drug therapy and other clinical interventions. Yet, developing general perioperative management as another crucial role operation room, pharmacists play and incorporating it into pharmaceutical education would be important. Enriching perioperative care provided by pharmacists can contribute toward improving the clinical competence of these professionals. Presently, there are no pharmacists in Zawia who participate in perioperative care. The objective of this study was to assess the pharmacist's knowledge of general anesthesia and drugs used to anesthetize patients who suffer from hypertension. A cross-sectional study was conducted in Zawia City, Tripoli in 2023. A self-designed questionnaire was distributed to 100 pharmacists. The study found that more than half of the pharmacists have humble knowledge about the drugs used in anesthesia, the findings indicated weakness in their information about drugs used to manage hypertension in surgery, and 36.0% know that sodium nitroprusside is used to control blood pressure during the operation. In conclusion, this study reported that some of the study's pharmacist participants had weak points that contributed to a high percentage of incorrect knowledge. These weak points may be attributable to poor educational preparation or a lack of training before the pharmacists began working in hospitals.

References

1. Hadi MA, Neoh CF, Zin RM, Elrggal ME, Cheema E (2017) Pharmacovigilance: pharmacists’ perspective on spontaneous adverse drug reaction reporting. Integrated Pharmacy Research and Practice. 6: 91-98. doi: 10.2147/ IPRP.S105881
2. Tefera GM, Zeleke AZ, Jima YM, Kebede TM (2020) Drug therapy problems and the role of clinical pharmacist in surgery ward: Prospective observational and interventional study. Drug Health and Patient Safety. 12: 71-83. doi: 10.2147/DHPS.S251200
3. Diao S, Ni J, Shi X, Liu P, Xia W (2014) Mechanisms of action of general anesthetics. Frontiers in Bioscience. 19 (5): 747-757. doi: 10.2741/4241
4. Estafanous FG (1989) Hypertension in the surgical patient: management of blood pressure and anesthesia. Cleveland Clinic Journal of Medicine. 56 (4): 385-393. doi: 10.3949/ccjm.56.4.385
5. Sonntag H, Hellberg K, Schenk HD, Donath U, Regensburger D, Kettler D, Larsen R (1975) Effects of thiopental (Trapanal) on coronary blood flow and myocardial metabolism in man. Acta Anaesthesiologica Scandinavica. 19 (1): 69-78. doi: 10.1111/j.1399-6576.1975.tb05224.x
6. Dundee JW (1974) Intravenous anaesthesia. Churchill Livingstone, distributed by Longman, Australia. ISBN: 0443009775.
7. Stanley TH, Bennett GM, Loeser EA, Kawamura R, Sentker CR (1976) Cardiovascular effects of diazepam and droperidol during morphine anesthesia. Anesthesiology. 44 (3): 255-260. doi: 10.1097/00000542-197603000-00019
8. Garcia P, Kolesky S, Jenkins A (2010) General anesthetic actions on GABA(A) receptors. Current Neuro-pharmacology. 8 (1): 2-9. doi: 10.2174/157015910790909502
9. Dagnino J, Prys-roberts C (1984) Studies of anaesthesia in relation to hypertension. VI: Cardiovascular responses to extradural blockade of treated and untreated hypertensive patients. British Journal of Anaesthesia. 56 (10): 1065-1073. doi: 10.1093/bja/56.10.1065
10. Goldman L, Caldera DL (1979) Risks of general anesthesia and elective operation in the hypertensive patient. Anesthesiology. 50 (4): 285-292. doi: 10.1097/00000542-197904000-00002
11. Reuven Pasternak L (1990) Anesthetic considerations in otolaryngological and ophthalmological outpatient surgery. International Anesthesiology Clinics. 28 (2): 89-100. doi: 10.1097/00004311-199002820-00005
12. Lauven PM, Helmut Schwilden H, Stoeckel H, Greenblatt DJ (1985) The effects of a benzodiazepine antagonist Ro 15-1788 in the presence of stable concentrations of midazolam. Anesthesiology. 63 (1): 61-64. doi: 10.1097/ 00000542-198507000-00009
13. Zambouri A (2007) Preoperative evaluation and preparation for anesthesia and surgery. Hippokratia. 11 (1): 13-21. PMID: 19582171; PMCID: PMC2464262.
14. Yancey R (2018) Anesthetic management of the hypertensive patient: Part II. Anesthesia Progress. 65 (3): 206-213. doi: 10.2344/anpr-65-03-17
15. Kulkarni S, O’Farrell I, Erasi M, Kochar MS (1988) Stress and hypertension. Wisconsin Medical Journal. 97 (11): 34-38. PMID: 9894438.
16. Carey RM, Cutler J, Friedewald W, Gant N, Hulley S, Iacono J (1984) The 1984 report of the joint national committee on detection, evaluation, and treatment of high blood pressure. Archives of Internal Medicine. 144 (5): 1045-1057. PMID: 6143542.
17. Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF, et al. (1999) Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 100 (10): 1043-1049. doi: 10.1161/01.cir.100.10.1043
18. Dingle HR (1966) Antihypertensive drugs and anesthesia. Anaesthesia. 21 (2): 151-172. doi 10.1111/j.1365-2044.1966.tb02595.x

Citation :

Ibraheim et al. (2023) Assessment of knowledge and attitude of pharmacists toward the side effects of anesthetics in patients with hypertension: a cross-sectional study. Mediterr J Pharm Pharm Sci. 3 (4): 97-105. https://doi.org/10.5281/zenodo.10443250

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