Body mass index and vitamin D in Libyan women

Abstract :

Vitamin D deficiency is a common health problem among Libyan women. Age, gender, inadequate exposure to sunlight, and obesity are common risk factors for this issue. In this study, we randomly examined 40 Libyan women (age: 17.58±10.45, mean ±SD, range: 15 years to 65 years). Blood samples were taken from each participant and directly centrifuged and processed on Cobas 411 Automatic Electrochemil-uminescence Immunoassay Analyzer. Vitamin D levels were measured in ng/ml and the mean serum value was calculated for the total. Body weight and height for each participant were taken to calculate the body mass index. The findings revealed that all participants are suffering from vitamin D deficiency with lesser than 30 ng/ml serum levels. Female participants aged between 55 and 65 years tend to have a less degree of vitamin D deficiency as compared to the other age subgroups with a mean level of 27 ng/ml of vitamin D. This study revealed the association between vitamin D levels and obesity as measured by body mass index, in contrast, it found that overweight participants have higher vitamin D levels as compared to other groups of body mass index.

References

1. Cowbrough K (2015) The importance of vitamin D. British Journal of Midwifery. 23 (7S): 3-4. doi: 10.12968/ bjom.2015.23.Sup7.3
2. Pedersen JI (2008) Vitamin D requirement and setting recommendation levels - current Nordic view. Nutrition Reviews. 66 (10 Suppl 2): S165-S169. doi: 10.1111/j.1753-4887.2008.00101.x
3. Armas LA, Hollis BW, Heaney RP (2004) Vitamin D2 is much less effective than vitamin D3 in humans. The Journal of Clinical Endocrinology and Metabolism. 89 (11): 5387-5391. doi: 10.1210/jc.2004-0360
4. Basit S (2013) Vitamin D in health and disease: a literature review. British Journal of Biomedical Science. 70 (4): 161-172. doi: 10.1080/09674845.2013.11669951
5. Alssageer MA, Alaasswad NM, Jebril AI, Ahmed HA, Almahdi RS (2022) Knowledge, attitude and practice of Libyan medical students about vitamin D deficiency. Mediterranean Journal of Pharmacy and Pharmaceutical Sciences. 2 (3): 46-56. doi: 10.5281/zenodo.7115292
6. Holick MF (2007) Vitamin D deficiency. The New England Journal of Medicine. 357 (3): 266-281. doi: 10.1056 /NEJMra070553
7. Elhadi AA, Ahmed AA (2022) Correlation of vitamin D with glycemic control and body mass index in patients with type II diabetes mellitus. Mediterranean Journal of Pharmacy and Pharmaceutical Sciences. 2 (1): 29-37. doi: 10.5281/zenodo.6399450
8. Msalati AA, Bashein A, Aljaloh E, Ghrew M, Sedaa K, Zaid A (2022) Prevalence of vitamin D deficiency in medical students. Mediterranean Journal of Pharmacy and Pharmaceutical Sciences. 2 (1): 73-82. doi: 10.5281/ zenodo.639978
9. Savastano S, Barrea L, Savanelli MC, Nappi F, Di Somma C, Orio F, Colao A (2017) Low vitamin D status and obesity: Role of nutritionist. Reviews in Endocrine and Metabolic Disorders. 18 (2): 215-225. doi: 10.1007/ s11154-017-9410-7
10. Malmberg HR, Hanel A, Taipale M, Heikkinen S, Carlberg C (2021) Vitamin D treatment sequence is critical for transcriptome modulation of immune challenged primary human cells. Frontiers in Immunology. 12: 754056. doi: 10.3389/fimmu.2021.754056
11. Heaney RP, Recker RR, Grote J, Horst RL, Armas LAG (2011) Vitamin D3 is more potent than vitamin D2 in humans. The Journal of Clinical Endocrinology and Metabolism. 96 (3): E447-E452. doi: 10.1210/jc.2010-2230
12. Pepper KJ, Judd SE, Nanes MS, Tangpricha V (2009) Evaluation of vitamin D repletion regimens to correct vitamin D status in adults. Endocrine Practice. 15 (2): 95-103. doi: 10.4158/EP.15.2.95
13. Poirier P (2007) Adiposity and cardiovascular disease: are we using the right definition of obesity?. European Heart Journal. 28 (17): 2047-2048. doi: 10.1093/eurheartj/ehm321
14. World Health Organization and World Obesity Federation (2018) Taking action on childhood obesity. Department of Prevention of Noncommunicable Diseases. World Health Organization, Geneva, Switzerland. https://iris.who.int/bitstream/handle/10665/274792/WHO-NMH-PND-ECHO-18.1-eng.pdf?ua=1.
15. Thomas DM, Bredlau C, Bosy-Westphal A, Mueller M, Shen W, Gallagher D, Maeda Y, McDougall A, Peterson CM, Ravussin E, Heymsfield SB (2013) Relationships between body roundness with body fat and visceral adipose tissue emerging from a new geometrical model. Obesity (Silver Spring, Md). 21 (11): 2264-2271. doi: 10.1002/oby.20408
16. Sanghera DK, Sapkota BR, Aston CE, Blackett PR (2017) Vitamin D status gender differences and cardio-metabolic health disparities. Annals of Nutrition and Metabolism. 70 (2): 79-87. doi: 10.1159/000458765
17. Heaney RP (2004) Functional indices of vitamin D status and ramifications of vitamin D deficiency. The American Journal of Clinical Nutrition. 80 (6S): 1706S-1709S. doi: 10.1093/ajcn/80.6.1706S
18. Snedecor G, Cochran W (1991) Statistical Methods, 8th ed., Oxford & IBH Publishing Co, New Delhi. 524. ISBN: 978-0-813-81561-9.
19. Pearce SH, Cheetham TD (2010) Diagnosis and management of vitamin D deficiency. British Medical Journal. 340: b5664. doi: 10.1136/bmj.b5664
20. Pereira-Santos M, Costa PR, Assis AM, Santos CA, Santos DB (2015) Obesity and vitamin D deficiency: a systematic review and meta-analysis. Obesity Reviews. 16 (4): 341-349. doi: 10.1111/obr.12239
21. Mosekilde L (2005) Vitamin D and the elderly. Clinical Endocrinology (Oxf). 62 (3): 265-281. doi: 10.1111/j. 1365-2265.2005.02226.x
22. Vanlint S (2013) Vitamin D and obesity. Nutrients. 5 (3): 949-956. doi: 10.3390/nu5030949
23. Ansari SA, Boker RA, Alsaid MS, Sherif RF, Sherif FM (2022) Analysis of association of vitamin D3, hemoglobin and ferritin with special respect to Libyan patients. Mediterranean Journal of Pharmacy and Pharmaceutical Sciences. 2 (4): 1-5. doi: 10.5281/zenodo.7479667
24. Nair R, Maseeh A (2012) Vitamin D: The "sunshine" vitamin. Journal Pharmacology and Pharmaco-therapeutics. 3 (2): 118-126. doi: 10.4103/0976-500X.95506

Citation :

Walli et al. (2024) Body mass index and vitamin D in Libyan women. Mediterr J Pharm Pharm Sci. 4 (2): 64-68. [Article Number: 160]. https://doi.org/10.5281/zenodo.12171291