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Received date : 12-01-2022 Revised date : 28-01-2022 Accepted date : 04-02-2022 Published date : 31-03-2022

Mediterr J Pharm Pharm Sci 2 (1): 29-37, 2022

DOI: https://doi.org/10.5281/zenodo.6399450

Original Research

Correlation of vitamin D with glycemic control and body mass index in patients with type II diabetes mellitus

Aboubaker A. Elhadi, Apoajela A. Ahmed

Vitamin D deficiency and its effect have attracted a considerable research interest due to its relation
to glucose homeostasis, insulin secretion, sensitivity and synthesis. The aim of this study was to evaluate
vitamin D levels in patients with type II diabetes mellitus aged between 35 - 65 years and investigating their
relations with glycemic control and obesity. The study included 74 Libyan patients with known history of type
II diabetes mellitus (33 males and 41 females). Serum glucose, glycosylated hemoglobin (HbA1c) and vitamin
D levels were biochemically estimated in these patients. Further, body mass index (BMI) was calculated for
all the diabetic patients (weight in kilogram per height in meter square). The mean level of plasma glucose
level was 150.58 ± 63.82 mg/dl (mean ± SD). The mean of HbA1c level was 7.90 ± 8.48% (mean ± SD). The
mean level of vitamin D was 22.7 5 ± 14.97 ng/ml. The mean of BMI was 26.55 ± 4.10 Kg per m2. The
findings showed that 58.10% of the cases had vitamin D deficiency (Out of which 24.24% were males and
85.36% were females). This study showed statistical significance differences in glucose, HbA1c, vitamin D
and BMI between male and female patients. Moreover, elderly ages for both sexes had adverse effects on
vitamin D status. Vitamin D levels have negatively been correlated with levels of glucose, HbA1c and BMI.
It is concluded that vitamin D deficiency has an adverse effect on glucose homeostasis in patients with type
II diabetes mellitus and this can be a contributor risk factor in complications of type II diabetes mellitus
development in Libyan patients.
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